Onchilles Pharma to Present Trial in Progress Poster at the 2026 ASCO Annual Meeting

April 21, 2026

SAN DIEGO, April 21, 2026 – Onchilles Pharma, a private biotech company advancing therapeutics targeting the ELANE pathway, today announced that it will present a trial in progress poster at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting.

Poster details are as follows:

Title: OP-NEU-101: A phase 1/2 open-label, dose finding and expansion study to investigate the safety and effectiveness and determine the optimal dose of N17350 administered intratumorally in participants with advanced solid tumors

Abstract Number: TPS2679

Session Title: Developmental Therapeutics, Immunotherapy

Presenter: Matteo Carlino, M.D.

Poster Board: 462a

Date and Time: May 30, 2026, 1:30 p.m. to 4:30 p.m. CDT

About Onchilles Therapeutic Programs Targeting the ELANE Pathway

At the core of this approach is the ELANE pathway, a unique cancer-selective killing mechanism that leverages a vulnerability shared by many cancer cell types: elevated histone H1 levels. Our pipeline is led by N17350, our first-in-class, clinical-stage program, followed by NEU-002, the second program that extends this approach with systemic delivery. By targeting the ELANE pathway and inducing immunogenic cancer cell death, N17350 and NEU-002 are designed to rapidly eliminate tumors while mobilizing an adaptive immune response, offering the potential for sustained anti-tumor immunity. N17350 and NEU-002 offer a unique approach to treating cancer regardless of their genetic makeup, anatomical origin, or immune status, positioning them as potential gamechangers in cancer therapy.

About Onchilles Pharma

Onchilles Pharma is a global drug discovery and development company pioneering first-in-class cytotoxic therapies designed to selectively kill cancer cells while preserving and activating immune function. By harnessing the ELANE pathway, these next-generation therapeutics are designed to deliver potent and selective tumor cell destruction, overcoming the limitations of traditional chemotherapy and immunotherapy. The company’s pipeline includes N17350, a tumor-directed lead candidate in first-in-human studies (ClinicalTrials.gov Identifier: NCT07339176), and the NEU-002 program for systemic delivery, extends the reach of N17350 to address all solid tumors. For more information, visit www.onchillespharma.com.

Contacts

Company: Peter Haberz, Ph.D., Vice President, Corporate Development, info@onchillespharma.com

Media: Jessica Yingling, Ph.D., Little Dog Communications Inc., jessica@litldog.com